AXON-TARGETING MOTIFS: MECHANISMS AND APPLICATIONS OF ENHANCING AXONAL LOCALISATION OF TRANSMEMBRANE PROTEINS

Axon-Targeting Motifs: Mechanisms and Applications of Enhancing Axonal Localisation of Transmembrane Proteins

Neuronal polarity established in developing neurons ensures proper function in the mature nervous system.As functionally distinct cellular compartments, axons and dendrites often require different subsets of proteins to maintain synaptic transmission and overall order.Although neurons in the mature CNS do not regenerate throughout life, their inter

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The effect of bovine dairy products and their components on the incidence and natural history of infection: a systematic literature review

Abstract Background Dairy products and their components may impact immune function, although the current evidence base has some research gaps.As part of a larger systematic literature review of dairy products/components (including probiotics, dairy proteins, and dairy fats) and immune function, we identified the available epidemiologic research on

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Selective influence of garlic as a key ingredient in kimchi on lactic acid bacteria in a fermentation model system

Garlic is an essential ingredient added to kimchi, a fermented vegetable, in small amounts owing to its sensory and antibacterial properties.This study aimed to elucidate the complex relationship between garlic and specific lactic acid bacteria (LAB) and the resulting metabolite changes in a controlled kimchi model system using nine strains as mixe

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Selective loss of slow and enhancement of fast Na+currents in cutaneous afferent dorsal root ganglion neurones following axotomy

Voltage-dependent Na+currents were recorded via patch-clamp from identified adult rat lumbar cutaneous dorsal root ganglion (DRG) neurones using whole-cell and bleb-patch-clamp configurations.Na+currents in DRG neurones studied 18 days after sciatic nerve ligation were compared with those in control neurones.Control neurones tended to have a singul

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